Digital Skin
Discovery
Pipeline
Contact
PELLICLE
Live
Skin is the largest organ. We made it computable.
247,841
molecules tested on digital skin
Each one replacing a €5,000 lab study. Running now.
Accuracy
0.84R²
Database
2,149measurements
Cost vs Lab
10,000×cheaper
To Patent
<48hours
Autoresearch Active
Screening Molecular Candidates
Passes Skin
Retained in SC
Rejected
SCREENED: 0
PASSED: 0
REJECTED: 0
RATE: 0 molecules/s
PASSED: 0
REJECTED: 0
RATE: 0 molecules/s
Stratum Corneum · 15μm
Live Simulation
Molecular Skin Journey
Validated Blind
67 compounds · R² = 0.84
PELLICLE · Digital Skin Engine
01
Discover
10,000 virtual skin tests overnight. Each replacing a €5,000 Franz cell study. Our autonomous pipeline generates candidates, searches patents, simulates permeation, scores safety and commercial viability. 10,000 in. 5 breakthroughs out.
02
Patent
Every discovery becomes IP. Composition-of-matter claims covering the molecule, its series, and its applications. We build portfolios that generate royalties for decades.
03
Earn
Partners synthesize, validate, and sell. We collect royalties on every kilogram. One successful ingredient: €200K–5M/year. The discoveries compound. The royalties compound.
First Discovery
N-Octyl Nicotinamide
Patent Pending
A prodrug of niacinamide — the $2.5B skincare active — engineered for 300× improved skin penetration. Releases niacinamide directly in the epidermis via skin amidases (t½ 5.2h). Discovered computationally. Validated by expert chemists. Entering synthesis.
Permeation
307×
vs niacinamide (validated)
Epidermis Delivery
26.5%
epidermis delivery
Concentration
Prodrug
amidase-activated in skin
Safety
Clean
low irritation, no phototox
Before & After
Niacinamide · the $2.5B active
-8.94
logKp · Very low permeation
Epidermis delivery: 33%
Requires 5-10% concentration
31.6% lost to systemic absorption
Requires 5-10% concentration
31.6% lost to systemic absorption
N-Octyl Nicotinamide Ours
-6.44
logKp · 307× faster
Epidermis delivery: 26.5%
Only 7.5% systemic (vs 31.6%)
Prodrug — amidase-activated in skin
Only 7.5% systemic (vs 31.6%)
Prodrug — amidase-activated in skin
Work With Us
Partner with us. We discover. You manufacture. We both earn.
We're looking for manufacturing partners — cosmetic brands, ingredient suppliers, and CDMOs who can synthesize, validate, and bring novel ingredients to market. We provide the discovery, the patent, and the science. You provide the lab and the shelf. Royalties are shared.